Dirk J Duncker Selected Research

Hypertrophy

10/2023	The microtubule signature in cardiac disease: etiology, disease stage, and age dependency.
1/2019	Cardiac remodelling in a swine model of chronic thromboembolic pulmonary hypertension: comparison of right vs. left ventricle.
12/2014	Gene reprogramming in exercise-induced cardiac hypertrophy in swine: A transcriptional genomics approach.
10/2014	The microRNA-15 family inhibits the TGFβ-pathway in the heart.
6/2011	Exercise training does not improve cardiac function in compensated or decompensated left ventricular hypertrophy induced by aortic stenosis.
4/2008	Extracellular superoxide dismutase protects the heart against oxidative stress and hypertrophy after myocardial infarction.
7/2005	Proteomic changes in the pressure overloaded right ventricle after 6 weeks in young rats: correlations with the degree of hypertrophy.

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Dirk J Duncker Research Topics

Disease

35	Myocardial Infarction 10/2023 - 06/2002
25	Infarction (Infarctions) 01/2017 - 04/2003
14	Ischemia 01/2020 - 07/2002
12	Heart Failure 03/2024 - 04/2003
10	Pulmonary Hypertension 01/2022 - 07/2006
7	Cardiovascular Diseases (Cardiovascular Disease) 10/2023 - 02/2012
7	Hypertrophy 10/2023 - 07/2005
7	Myocardial Ischemia (Ischemic Heart Diseases) 01/2020 - 07/2008
6	Hypertension (High Blood Pressure) 10/2023 - 01/2012
6	Hypoxia (Hypoxemia) 01/2022 - 05/2012
5	Left Ventricular Dysfunction 03/2024 - 06/2002
5	Atherosclerosis 10/2023 - 12/2002
5	Diabetes Mellitus 12/2021 - 01/2015
5	Fibrosis (Cirrhosis) 09/2020 - 04/2008
5	Coronary Occlusion 01/2017 - 02/2006
4	Coronary Artery Disease (Coronary Atherosclerosis) 01/2024 - 11/2016
4	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 01/2023 - 11/2016
4	Vascular Diseases (Vascular Disease) 01/2022 - 03/2017
4	Pulmonary Arterial Hypertension 01/2022 - 01/2018
4	Hypercholesterolemia 12/2021 - 12/2013
4	ST Elevation Myocardial Infarction 01/2020 - 10/2013
4	Inflammation (Inflammations) 01/2019 - 06/2003
4	Reperfusion Injury 09/2015 - 06/2004
4	Ganglion Cysts (Ganglion) 07/2005 - 07/2002
3	Cardiotoxicity 01/2021 - 01/2012
3	Hyperemia 04/2017 - 03/2010
3	Necrosis 08/2015 - 07/2013
2	Disease Progression 01/2024 - 01/2021
2	Neointima 01/2023 - 01/2020
2	Chronic Renal Insufficiency 12/2021 - 01/2021
2	Neoplasms (Cancer) 01/2021 - 09/2018
2	Glycogen Storage Disease Type II (Pompe's Disease) 06/2020 - 07/2010
2	Cardiomegaly (Heart Hypertrophy) 01/2020 - 06/2007
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 10/2017
2	Heart Diseases (Heart Disease) 01/2020 - 01/2008
2	Kidney Diseases (Kidney Disease) 11/2019 - 01/2019
2	Cardiomyopathies (Cardiomyopathy) 12/2017 - 04/2015
2	Insulin Resistance 07/2017 - 11/2014
2	Thrombosis (Thrombus) 10/2016 - 05/2010
2	Cicatrix (Scar) 08/2015 - 08/2012
2	Body Weight (Weight, Body) 01/2015 - 07/2005
2	Pathologic Constriction (Stenosis) 04/2013 - 04/2008
2	Aneurysm (Aneurysms) 01/2011 - 03/2007
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 10/2023

Drug/Important Bio-Agent (IBA)

16	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2022 - 06/2002
11	Proteins (Proteins, Gene)FDA Link 01/2019 - 07/2005
10	Endothelins (Endothelin)IBA 12/2021 - 02/2005
10	Oxygen (Dioxygen)IBA 01/2020 - 03/2010
10	Vasodilator Agents (Vasodilators)IBA 10/2018 - 06/2002
9	Vasoconstrictor AgentsIBA 12/2021 - 07/2006
7	Biomarkers (Surrogate Marker)IBA 03/2024 - 01/2012
7	Nitric Oxide Synthase (NO Synthase)IBA 12/2017 - 06/2002
7	Adenosine Triphosphate (ATP)IBA 10/2017 - 06/2002
7	Adenosine (Adenocard)FDA LinkGeneric 05/2017 - 07/2002
5	salicylhydroxamic acid (SHAM)IBA 01/2022 - 01/2008
5	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 01/2020 - 04/2003
4	Streptozocin (Streptozotocin)FDA Link 12/2021 - 01/2015
4	Phosphotransferases (Kinase)IBA 01/2021 - 03/2008
4	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 01/2019 - 05/2013
3	CytokinesIBA 12/2021 - 08/2015
3	uridine adenosine tetraphosphateIBA 01/2019 - 11/2013
3	beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA 05/2017 - 07/2005
3	Norepinephrine (Noradrenaline)FDA LinkGeneric 12/2013 - 10/2002
3	Dobutamine FDA LinkGeneric 09/2012 - 06/2010
3	Angiotensin IIIBA 05/2008 - 10/2002
3	Hexamethonium (Hexamethonium Bromide)IBA 07/2005 - 07/2002
2	LipidsIBA 01/2024 - 01/2022
2	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 12/2014
2	Matrix Metalloproteinases (MMPs)IBA 09/2020 - 10/2003
2	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 11/2014
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2020 - 07/2014
2	Endothelin-1 (Endothelin 1)IBA 12/2018 - 04/2008
2	Hemoglobins (Hemoglobin)IBA 05/2017 - 03/2010
2	HBOC 201 (Hemopure)IBA 05/2017 - 03/2010
2	Nitroglycerin (Dynamite)FDA LinkGeneric 05/2017 - 11/2014
2	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2017 - 01/2008
2	CholesterolIBA 11/2016 - 12/2002
2	Fatty Acid Binding Protein 3IBA 02/2016 - 10/2013
2	CollagenIBA 08/2015 - 06/2011
2	Troponin IIBA 10/2013 - 01/2008
2	Adrenergic Agents (Adrenergic Drugs)IBA 04/2012 - 03/2011
2	Tyrosine (L-Tyrosine)FDA Link 01/2012 - 06/2004
2	ProstaglandinsIBA 09/2011 - 05/2007
2	Atrial Natriuretic Factor (ANF)IBA 06/2011 - 04/2008
2	fibulinIBA 01/2011 - 03/2007
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 03/2008 - 06/2004
2	Purinergic P1 Receptors (Adenosine Receptor)IBA 01/2008 - 07/2002
2	Pentobarbital (Nembutal)FDA Link 03/2007 - 07/2005
1	Indicators and Reagents (Reagents)IBA 03/2024
1	TubulinIBA 10/2023
1	DesminIBA 10/2023

Therapy/Procedure

18	Therapeutics 10/2023 - 07/2006
6	Drug-Eluting Stents 01/2023 - 06/2005
5	Stents 01/2023 - 06/2003
5	Percutaneous Coronary Intervention 01/2021 - 01/2012
5	Ligation 01/2011 - 09/2005
2	Microspheres (Microsphere) 01/2018 - 08/2015
2	Vagus Nerve Stimulation 09/2015 - 07/2006
2	Transplantation 05/2010 - 06/2005
1	Precision Medicine 10/2023